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, 2001). This constrained malignant development relates prominently to the activation of p53 in aspiring cancer cells going through telomere dysfunction. Inactivation in the p53 tumor suppressor is The most frequent functions in human epithelial cancers (Brosh and Rotter, 2009) as well as the position of p53 can dictate no matter if telomere dysfun
Telomeres as protecting "caps" on the tips of eukaryotic chromosomes. How telomerase extends telomeres.Telomerase is not really ordinarily active in the majority of somatic cells (cells with the body), nonetheless it’s active in germ cells (the cells that make sperm and eggs) and many Grownup stem cells.-dependent therapeutic vaccination have res